Chronic Myeloproliferative Syndromes
These are diseases in which bone marrow hematopoietic stem cells produce more mature elements than normal: leukocytes (chronic myeloid leukemia), red blood cells or erythrocytes (polycythemia vera) and platelets (essential thrombocythemia). Another disease included in this group is primary myelofibrosis.
This is a group of diseases with varied clinical evolution and prognosis that are produced to abnormalitiers in the functioning of the hematopoietic stem cells that produce less mature elements in peripheral blood, with a defective function. They are mainly characterized by the presence of anemia.
Amongst them we can distinguish chronic lymphocytic leukemia, in which there is an increase in leukocytes and lymphocytes in peripheral blood and lymphomas, which are diseases of the lymph nodes with different histologies, clinical behavior and course and requiring very different treatment modalities.
Monoclonal Gammopathies (multiple myeloma and other plasma cell diseases)
These are diseases produced by the abnormal function of plasma cells. They generally affect elderly patients. From the clinical point of view they are characterized by the presence of bone pain, anemia and, occasionally, renal function impairment and an increase of calcium in the blood. Their prognosis has improved significantly in recent years due to the introduction of new drugs.
A decrease in peripheral blood leukocyte counts.
Decreased hemoglobin and circulating red blood cells. Anemia can be congenital (detected from birth) or acquired. Among the acquired types, the most frequent ones are those related to iron and other vitamin deficiencies, or the excessive destruction of red blood cells (hemolytic anemias).
A decreased number of platelets in peripheral blood. Thrombocytopenia may be due to a lack of platelet production in bone marrow (central thrombopenia) or an increase in their destruction in peripheral blood (peripheral thrombopenia).
These diseases are characterized by the presence of low levels of immunoglobulins, either one or several, which in many cases leads to an increase in the vulnerability to infectious complications.
A hereditary disease in which iron accumulates in excessive amounts in tissues.
HEMOSTASIA ABD THROMBOSIS
This area of knowledge encompasses diseases leading to thrombosis and/or bleeding. It includes the Thrombosis Clinic, Reproduction and Thrombophilia Unit, as well as the Coagulopathies Unit.
An innovative Clinic ensuring excellent, personalized attention. Through coordination by a hematologist, the patient presenting a venous or arterial thrombosis receives multidisciplinary attention to prevent a new thrombosis-related episode, from the moment he is admitted until his discharge.
In addition, this clinic conducts genetic studies of thrombophilia to determine the possible cause of the thrombosis and to offer each patient the best anticoagulant treatment in the short, medium and long term.
REPRODUCTION AND THROMBOPHILIA UNIT
Miscarriages, and the appearance of complications during pregnancy, such as preeclampsia, placental insufficiency or fetal death in the final phases of gestation, are associated with the presence of thrombophilic genetic factors. In this unit a genetic test is offered with more than 11 mutations related to the risk of complications during pregnancy. At present there is a prothrombotic biomarker in the blood of both the father and the mother that can help to identify those women who can benefit most from an anti-thrombosis treatment. At our Unit we can offer you the latest medical advances in the field of thrombophilia and reproduction.
We work jointly with the Department of Obstetrics led by Dr. Serra and with the Department of Reproductive Medicine led by Dr. Coroleu, with the collaboration of Dra. Buxaderas.
Congenital or Acquired Coagulopathies are diagnosed and treated. They make the patient susceptible to suffer hemorrhagic processes, such as: abundant periods, nosebleeds, or frequent bruising, which can be due to congenital diseases, such as von Willebrand's Disease, hemophilia, platelet disorders, kidney or liver disease, or disorders affecting other organs.